Hang-over-and-headaches

• fatigue,
• back and neck pain,
• headaches,
• hypersensitivity to noise and light,
• intense thirst.

Furthermore, due to its diuretic effect related to the inhibition of antidiuretic hormone secretion, alcohol mobilizes the body's water reserves more. 

Restoring fluid and mineral metabolism is essential.

Don't wait until you're thirsty because it will be too late. 

Electrolytes

To meet the body's needs, HANG-OVER contains a suitable rehydration solution, based on electrolytes (Chloride, Potassium, Sodium). 

The role of electrolytes is to combat cellular dehydration recorded after alcohol intake. The body has a wide variety of electrolytes: Sodium, Potassium, Calcium, Bicarbonate, Magnesium, Chloride, and Phosphate. Each electrolyte serves a purpose: sodium, for example, regulates, among other things, water movements in the body.

Alcohol consumption induces an imbalance of these electrolytes. Indeed, they are mobilized to eliminate toxic metabolites of ethanol. What has been consumed must be reabsorbed to restore vital fluid balance. 

It is common to find acute alcohol intoxication as a reason for admission to hospital emergency departments. To best assess the patient's needs, a blood test identifies the electrolytes that have been affected. Excessive water elimination is the cause of the disturbance in the biological balance, as our electrolytes are eliminated in urine.[2,3]  In this regard, it has been noticed that during alcohol consumption, the level of magnesium in the blood tends to increase - that's why HANG-OVER does not contain it. 

Thus, oral rehydration seems essential in the management of this hyperosmolar dehydration. The electrolyte concentration must comply with recommendations in the case of pathological dehydration. We are therefore inspired by the WHO recommendations for our composition.

Ginger

Ginger has interesting anti-inflammatory properties in the management of migraines induced by veisalgie. An study highlights that the intake of standardized ginger powder at a dose of 500-600 mg, 3 to 4 times a day every 4 hours, can relieve a migraine. [4]

Restoring electrolyte balance and the anti-inflammatory action of ginger will help reduce headaches.

[1] Irwin C, Leveritt M, Shum D, Desbrow B. The effects of dehydration, moderate alcohol consumption, and rehydration on cognitive functions. Alcohol. 2013 May;47(3):203-13. doi: 10.1016/j.alcohol.2012.12.016. Epub 2013 Jan 23. PMID: 23352231.

[2] Joannidis M, Cantley L (2000) Kidney and electrolyte disturbances, chap 19. In: Zernig G, Saria A, Kurz M, O’Malley SS (eds) Handbook of alcoholism. Boca Raton, Fla, CRC Press, pp 209–224. 

[3] Ragland G (1990) Electrolyte abnormalities in the alcoholic patient. Emerg Med Clin North Am 8: 761–773

[4] Mustafa T, Srivastava KC. Ginger (Zingiber officinale) in migraine headache. J Ethnopharmacol. 1990;29:267–73